GLI1 anticorps

N° du produit ABIN7248113

L’anticorps Lapin Polyclonal anti-GLI1 a été validé pour WB, ELISA et IHC. Il convient pour détecter GLI1 dans des échantillons de Humain et Souris.

Aperçu rapide pour GLI1 anticorps (ABIN7248113)

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLI1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GLI1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human GLI1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.08 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GLI1

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Autre désignation: GLI1

Sujet: GLI1 (GLI Family Zinc Finger 1) is a Protein Coding gene. Diseases associated with GLI1 include Basal Cell Carcinoma and Necrobiosis Lipoidica. Among its related pathways are Wnt Signaling Pathways: beta-Catenin-independent Wnt/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways and G-Beta Gamma Signaling. GO annotations related to this gene include chromatin binding and microtubule binding. An important paralog of this gene is GLI2. This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 118 kDa

UniProt: P08151

Pathways: Signalisation Hedgehog, Dopaminergic Neurogenesis